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1

Antiviral Pathway Activation in Chronic Fatigue Syndrome and Acute Infection

De Meirleir, Kenny, Suhadolnik, Robert J., Lebleu, Bernard, Englebienne, Patrick

Journal:

Clinical Infectious Diseases

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

2

Dynamics of detachment of Escherichia coli from plasma-mediated coatings under shear flow

Mercier-Bonin, Muriel, Duviau, Marie-Pierre, Ellero, Christophe, Lebleu, Nathalie, Raynaud, Patrice, Despax, Bernard, Schmitz, Philippe

Journal:

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

3

Assessment of High-Affinity Hybridization, RNase H Cleavage, and Covalent Linkage in Translation Arrest by Antisense Oligonucleotides

GEE, JAY E., ROBBINS, IAN, VAN DER LAAN, ALEXANDER C., VAN BOOM, JACQUES H., COLOMBIER, CAROLINE, LENG, MARC, RAIBLE, ANNETTE M., NELSON, JEFFREY S., LEBLEU, BERNARD

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1998

Language:

english

File:

PDF, 10.78 MB

english, 1998

4

Impact of the Guanidinium Group on Hybridization and Cellular Uptake of Cationic Oligonucleotides

Gaëlle Deglane, Saïd Abes, Thibaut Michel, Paul Prévot, Eric Vives, Françoise Debart, Ivan Barvik, Bernard Lebleu, Jean-Jacques Vasseur

Journal:

Year:

2006

Language:

english

File:

PDF, 762 KB

english, 2006

5

Switching on transgene expression by correcting aberrant splicing using multi-targeting steric-blocking oligonucleotides

Sarah Resina, Ryszard Kole, Adrian Travo, Bernard Lebleu, Alain R. Thierry

Journal:

The Journal of Gene Medicine

Year:

2007

Language:

english

File:

PDF, 392 KB

english, 2007

6

Regeneration of enzyme activity after Western blot: Activation of RNase L by 2-5A on filter— Importance for its detection

Tamim Salehzada, Michelle Silhol, Bernard Lebleu, Catherine Bisbal

Journal:

Analytical Biochemistry

Year:

1991

Language:

english

File:

PDF, 1.44 MB

english, 1991

7

4981957 Oligonucleotides with modified phosphate and modified carbohydrate moieties at the respective chain termini

Bernard Lebleu, Bernard Bayard

Journal:

International Journal of Biochemistry

Year:

1991

Language:

english

File:

PDF, 107 KB

english, 1991

8

Lipoplex and peptide-based strategies for the delivery of steric-block oligonucleotides

Sarah Resina, Saïd Abes, John J. Turner, Paul Prevot, Adrian Travo, Philippe Clair, Michael J. Gait, Alain R. Thierry, Bernard Lebleu

Journal:

International Journal of Pharmaceutics

Year:

2007

Language:

english

File:

PDF, 658 KB

english, 2007

9

Toward high yield synthesis of peptide–oligonucleotide chimera through a disulfide bridge: A simplified method for oligonucleotide activation

Frédéric Maurel, Françoise Debart, Florine Cavelier, Alain R. Thierry, Bernard Lebleu, Jean-Jacques Vasseur, Eric Vivès

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 223 KB

english, 2005

10

One-pot labeling and purification of peptides and proteins with fluorescein maleimide

Eric Vivès, Bernard Lebleu

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 107 KB

english, 2003

11

Selective coupling of a highly basic peptide to an oligonucleotide

Eric Vivès, Bernard Lebleu

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 224 KB

english, 1997

12

Oligonucléotides antisens en chimiothérapie antivirale : problèmes et perspectives d'utilisation

Ian Robbins, Lionel Bastide, Bernard Lebleu

Journal:

Revue Française des Laboratoires

Year:

1998

File:

PDF, 1.88 MB

1998

13

Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat

Michelle Silhol, Mudit Tyagi, Mauro Giacca, Bernard Lebleu, Eric Vivès

Journal:

Year:

2002

Language:

english

File:

PDF, 349 KB

english, 2002

14

Structure-activity relationship study of the plasma membrane translocating potential of a short peptide from HIV-1 Tat protein

Eric Virès, Claude Granier, Paul Prevot, Bernard Lebleu

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1997

Language:

english

File:

PDF, 979 KB

english, 1997

15

Modulation of nucleic acid information processing by PNAs: potential use in anti-viral therapeutics

Lionel Bastide, Bernard Lebleu, Ian Robbins

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 1.32 MB

english, 2003

16

Cell penetrating peptides: overview and applications to the delivery of oligonucleotides

F. Said Hassane, A. F. Saleh, R. Abes, M. J. Gait, Bernard Lebleu

Journal:

Cellular and Molecular Life Sciences

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

17

Modulation of nucleic acid information processing by PNAs: Potential use in anti-viral therapeutics

Lionel Bastide, Bernard Lebleu, Ian Robbins

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2005

Language:

english

File:

PDF, 289 KB

english, 2005

18

Preface

Gillian Barratt, Didier Betbeder, Bernard Lebleu

Journal:

International Journal of Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

19

Structure–activity relationship study of the plasma membrane translocating potential of a short peptide from HIV-1 Tat protein

Eric Vivès, Claude Granier, Paul Prevot, Bernard Lebleu

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1997

Language:

english

File:

PDF, 1.41 MB

english, 1997

20

Delivering information-rich drugs -prospects and challenges

Journal:

Trends in Biotechnology

Year:

1996

Language:

english

File:

PDF, 287 KB

english, 1996

21

Tat peptide-mediated cellular delivery: back to basics

Hilary Brooks, Bernard Lebleu, Eric Vivès

Journal:

Advanced Drug Delivery Reviews

Year:

2005

Language:

english

File:

PDF, 232 KB

english, 2005

22

Cell penetrating peptide conjugates of steric block oligonucleotides

Bernard Lebleu, Hong M. Moulton, Rachida Abes, Gabriela D. Ivanova, Said Abes, David A. Stein, Patrick L. Iversen, Andrey A. Arzumanov, Michael J. Gait

Journal:

Advanced Drug Delivery Reviews

Year:

2008

Language:

english

File:

PDF, 467 KB

english, 2008

23

Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates

Saïd Abes, Donna Williams, Paul Prevot, Alain Thierry, Michael J. Gait, Bernard Lebleu

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 720 KB

english, 2006

24

Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents

Saïd Abes, Hong M. Moulton, Philippe Clair, Paul Prevot, Derek S. Youngblood, Rebecca P. Wu, Patrick L. Iversen, Bernard Lebleu

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 857 KB

english, 2006

25

A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides

Sara Trabulo, Sarah Resina, Sérgio Simões, Bernard Lebleu, Maria C. Pedroso de Lima

Journal:

Journal of Controlled Release

Year:

2010

Language:

english

File:

PDF, 996 KB

english, 2010

26

Insights into the cellular trafficking of splice redirecting oligonucleotides complexed with chemically modified cell-penetrating peptides

Fatouma Said Hassane, Rachida Abes, Samir EL Andaloussi, Taavi Lehto, Rannar Sillard, Ülo Langel, Bernard Lebleu

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 751 KB

english, 2011

27

Systemic delivery of BH4 anti-apoptotic peptide using CPPs prevents cardiac ischemia–reperfusion injuries in vivo

Prisca Boisguerin, Christelle Redt-Clouet, Alicia Franck-Miclo, Sana Licheheb, Joël Nargeot, Stéphanie Barrère-Lemaire, Bernard Lebleu

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 863 KB

english, 2011

28

RNase L inhibitor (RLI) antisense constructions block partially the down regulation of the 2-5A/RNase L pathway in encephalomyocarditis-virus-(EMCV)-infected cells

Camille Martinand, Tamim Salehzada, Michelle Silhol, Bernard Lebleu, Catherine Bisbal

Journal:

Year:

1998

Language:

english

File:

PDF, 393 KB

english, 1998

29

Subcellular distribution of 2′,5′-oligoadenylate synthetase in differentiating Friend leukemia cells

Nadir Mechti, Elisabetta Affabris, Gianna Romeo, Bernard Lebleu

Journal:

Differentiation

Year:

1985

Language:

english

File:

PDF, 361 KB

english, 1985

30

Characterization of the Messenger Ribonucleoprotein Released from Reticulocyte Polyribosomes by EDTA Treatment

Bernard Lebleu, Gérard Marbaix, Georges Huez, Jacques Temmerman, Arsène Burny, Hubert Chantrenne

Journal:

Year:

1971

Language:

english

File:

PDF, 527 KB

english, 1971

31

Messenger Ribonucleoprotein and Initiation Factors in Rabbit-Reticulocyte Polyribosomes

Uri Nudel, Bernard Lebleu, Michel Revel, Tova Zehavi-Willner

Journal:

Year:

1973

Language:

english

File:

PDF, 719 KB

english, 1973

32

Structure of Globin mRNA and mRNA-Protein Particles : Use of Dark-Field Electron Microscopy

Jacques Dubochet, Carlos Morel, Bernard Lebleu, Max Herzberg

Journal:

Year:

1973

Language:

english

File:

PDF, 2.38 MB

english, 1973

33

Blocks in Elongation and Initiation of Protein Synthesis Induced by Interferon Treatment in Mouse L Cells

Jean CONTENT, Uri NUDEL, Asher ZILBERSTEIN, Hanna BERISSI, Michel REVEL, Bernard LEBLEU

Journal:

Year:

1975

Language:

english

File:

PDF, 947 KB

english, 1975

34

Interferon, Double-Stranded RNA and RNA Degradation : Characteristics of an Endonuclease Activity

Lee RATNER, Ganes C. SEN, Glenn E. BROWN, Bernard LEBLEU, Masao KAWAKITA, Bartolome CABRER, Elizabeth SLATTERY, Peter LENGYEL

Journal:

Year:

1977

Language:

english

File:

PDF, 1.15 MB

english, 1977

35

Increased stability and antiviral activity of 2′-O-phosphoglyceryl derivatives of (2′-5′)oligo(adenylate) : Roles of phosphodiesterases and phosphatases in (2′-5′)oligo(adenylate) catabolism

Bernard BAYARD, Catherine BISBAL, Michele SILHOL, Joël CNOCKAERT, Georges HUEZ, Bernard LEBLEU

Journal:

Year:

1984

Language:

english

File:

PDF, 750 KB

english, 1984

36

Antiviral activity in L1210 cells of liposome-encapsulated (2′-5′)oligo(adenylate) analogues

Bernard BAYARD, Lee D. LESERMAN, Catherine BISBAL, Bernard LEBLEU

Journal:

Year:

1985

Language:

english

File:

PDF, 681 KB

english, 1985

37

Characterization of two murine (2′-5′)(A)n-dependent endonucleases of different molecular mass

Catherine BISBAL, Tamim SALEHZADA, Bernard LEBLEU, Bernard BAYARD

Journal:

Year:

1989

Language:

english

File:

PDF, 1.10 MB

english, 1989

38

Antibody targeted liposomes containing poly(rI) · poly(rC) exert a specific antiviral and toxic effect on cells primed with interferons α/β or γ

Pierre G. Milhaud, Patrick Machy, Bernard Lebleu, Lee Leserman

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1989

Language:

english

File:

PDF, 463 KB

english, 1989

39

Microinjected interferon does not promote an antiviral response in Hela cells

Georges Huez, Michèle Silhol, Bernard Lebleu

Journal:

Biochemical and Biophysical Research Communications

Year:

1983

Language:

english

File:

PDF, 248 KB

english, 1983

40

Interferon-induced early changes in nuclear protein interactions with the interferon consensus sequence

Christian Roy, Bernard Lebleu

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 1.47 MB

english, 1989

41

Comparison of basic peptides- and lipid-based strategies for the delivery of splice correcting oligonucleotides

Alain R. Thierry, Said Abes, Sarah Resina, Adrian Travo, Jean Philippe Richard, Paul Prevot, Bernard Lebleu

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2006

Language:

english

File:

PDF, 445 KB

english, 2006

42

Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis

Marita Overhoff, Martina Alken, Rosel Kretschmer-Kazemi Far, Marc Lemaitre, Bernard Lebleu, Georg Sczakiel, Ian Robbins

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 327 KB

english, 2005

43

A 37 kDa 2-5A binding protein as a potential biochemical marker for chronic fatigue syndrome

Kenny De Meirleir, Catherine Bisbal, Isabelle Campine, Pascale De Becker, Tamim Salehzada, Edith Demettre, Bernard Lebleu

Journal:

The American Journal of Medicine

Year:

2000

Language:

english

File:

PDF, 387 KB

english, 2000

44

Selective mRNA degradation by antisense oligonucleotide-2,5A chimeras: Involvement of RNase H and RNase L

Ian Robbins, Guillaume Mitta, Sylvie Vichier-Guerre, Robert Sobol, Anna Ubysz, Bernard Rayner, Bernard Lebleu

Journal:

Year:

1998

Language:

english

File:

PDF, 1.59 MB

english, 1998

45

cDNA cloning and expression analysis of the murine ribonuclease L inhibitor

Amélie Benoit De Coignac, Catherine Bisbal, Bernard Lebleu, Tamim Salehzada

Journal:

Year:

1998

Language:

english

File:

PDF, 927 KB

english, 1998

46

Imporved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide

Bongartz, Jean-Pierre, Aubertain, Anne-Marie, Milhaud, Pierre G., Lebleu, Bernard

Journal:

Nucleic Acids Research

Year:

1994

Language:

english

File:

PDF, 2.18 MB

english, 1994

47

Antisense inhibitors of HIV: Problems and perspectives

Geneviève Degols, Jean-Paul Leonetti, Pierre Milhaud, Nadir Mechti, Bernard Lebleu

Journal:

Antiviral Research

Year:

1992

Language:

english

File:

PDF, 553 KB

english, 1992

48

Modulation of nucleic acid information processing by PNAs: potential use in anti-viral therapeutics

Lionel Bastide, Bernard Lebleu, Ian Robbins

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 284 KB

english, 2003

49

Sequence-Specific Activity of Antisense Oligonucleotides Conjugated to Poly (l-Lysine) Carriers

GENEVIÈVE DEGOLS, JEAN-PAUL LEONETTI, BERNARD LEBLEU

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 145 KB

english, 1992

50

Phosphorothioate analogs of (2'-5')(A)4: agonist and antagonist activities in intact cells

Charachon, Guillaume, Sobol, Robert W., Bisbal, Catherine, Salehzada, Tamim, Silhol, Michele, Charubala, Ramamurthy, Pfleiderer, Wolfgang, Lebleu, Bernard, Suhadolnik, Robert J.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.58 MB

english, 1990